Analysis Note

ControlSK-MEL-28 cell lysate

Application

Detect SOX10 using this Anti-SOX10 antibody, clone 12H6.1 validated for use in western blotting.

Research Sub CategoryDevelopmental NeuroscienceNeurodegenerative Diseases

Research CategoryStem Cell ResearchNeuroscience

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Transcription factor SOX10 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Sox10 acts as a nucleocytoplasmic shuttle protein and is important for neural crest, glial and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Immunogen

KLH-conjugated linear peptide corresponding to Human SOX10.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Protein G Purified

Purified mouse monoclonal IgG1κ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Format: Purified

Quality

Evaluated by Western Blot in a SK-MEL-28 cell lysate. Western Blot Analysis: A 1:2000 dilution of this antibody detected SOX10 in a 10 µg SK-MEL-28 cell lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~55 kDa observed